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The general goal of our laboratory is to understand normal and pathological effects of mechanical factors on the structure and function of human tissues, with an emphasis on the musculoskeletal system. The research conducted in the Musculoskeletal Biomechanics Lab, under the direction of Prof. Amit Gefen, is unified under the umbrella of integrated biomechanics, and utilizes state-of-the-art experimental, analytical, and numerical simulation techniques. Work in the laboratory has yielded fundamental information about adaptation and damage phenomena in bone and soft tissues.